Publications

all Publications


Li, J., Pinto-Duarte, A., Zander, M., Cuoco, M.S., Lai, C.Y., Osteen, J., Fang, L., Luo, C., Lucero, J.D., Gomez-Castanon, R., Nery, J.R., Silva-Garcia, I., Pang, Y., Sejnowski, T.J., Powell, S.B., Ecker, J.R., Mukamel, E.A., Behrens, M.M. knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3. (2022) Elife. 11. DOI: 10.7554/eLife.66909

+ expand abstract

Luo, C., Liu, H., Xie, F., Armand, E.J., Siletti, K., Bakken, T.E., Fang, R., Doyle, W.I., Stuart, T., Hodge, R.D., Hu, L., Wang, B.A., Zhang, Z., Preissl, S., Lee, D.S., Zhou, J., Niu, S.Y., Castanon, R., Bartlett, A., Rivkin, A., Wang, X., Lucero, J., Nery, J.R., Davis, D.A., Mash, D.C., Satija, R., Dixon, J.R., Linnarsson, S., Lein, E., Behrens, M.M., Ren, B., Mukamel, E.A., Ecker, J.R. Single nucleus multi-omics identifies human cortical cell regulatory genome diversity. (2022) Cell Genom. 2(3). DOI: 10.1016/j.xgen.2022.100107

+ expand abstract

Liu, H., Zhou, J., Tian, W., Luo, C., Bartlett, A., Aldridge, A., Lucero, J., Osteen, J.K., Nery, J.R., Chen, H., Rivkin, A., Castanon, R.G., Clock, B., Li, Y.E., Hou, X., Poirion, O.B., Preissl, S., Pinto-Duarte, A., O’Connor, C., Boggeman, L., Fitzpatrick, C., Nunn, M., Mukamel, E.A., Zhang, Z., Callaway, E.M., Ren, B., Dixon, J.R., Behrens, M.M., Ecker, J.R. DNA methylation atlas of the mouse brain at single-cell resolution. (2021) Nature. 598(7879):120-128. DOI: 10.1038/s41586-020-03182-8

+ expand abstract

Zhang, Z., Zhou, J., Tan, P., Pang, Y., Rivkin, A.C., Kirchgessner, M.A., Williams, E., Lee, C.T., Liu, H., Franklin, A.D., Miyazaki, P.A., Bartlett, A., Aldridge, A.I., Vu, M., Boggeman, L., Fitzpatrick, C., Nery, J.R., Castanon, R.G., Rashid, M., Jacobs, M.W., Ito-Cole, T., O’Connor, C., Pinto-Duartec, A., Dominguez, B., Smith, J.B., Niu, S.Y., Lee, K.F., Jin, X., Mukamel, E.A., Behrens, M.M., Ecker, J.R., Callaway, E.M. Epigenomic diversity of cortical projection neurons in the mouse brain. (2021) Nature. 598(7879):167-173. DOI: 10.1038/s41586-021-03223-w

+ expand abstract

Li, Y.E., Preissl, S., Hou, X., Zhang, Z., Zhang, K., Qiu, Y., Poirion, O.B., Li, B., Chiou, J., Liu, H., Pinto-Duarte, A., Kubo, N., Yang, X., Fang, R., Wang, X., Han, J.Y., Lucero, J., Yan, Y., Miller, M., Kuan, S., Gorkin, D., Gaulton, K.J., Shen, Y., Nunn, M., Mukamel, E.A., Behrens, M.M., Ecker, J.R., Ren, B. An atlas of gene regulatory elements in adult mouse cerebrum. (2021) Nature. 598(7879):129-136. DOI: 10.1038/s41586-021-03604-1

+ expand abstract

Yao, Z., Liu, H., Xie, F., Fischer, S., Adkins, R.S., Aldridge, A.I., Ament, S.A., Bartlett, A., Behrens, M.M., Van den Berge, K., Bertagnolli, D., de Bézieux, H.R., Biancalani, T., Booeshaghi, A.S., Bravo, H.C., Casper, T., Colantuoni, C., Crabtree, J., Creasy, H., Crichton, K., Crow, M., Dee, N., Dougherty, E.L., Doyle, W.I., Dudoit, S., Fang, R., Felix, V., Fong, O., Giglio, M., Goldy, J., Hawrylycz, M., Herb, B.R., Hertzano, R., Hou, X., Hu, Q., Kancherla, J., Kroll, M., Lathia, K., Li, Y.E., Lucero, J.D., Luo, C., Mahurkar, A., McMillen, D., Nadaf, N.M., Nery, J.R., Nguyen, T.N., Niu, S.Y., Ntranos, V., Orvis, J., Osteen, J.K., Pham, T., Pinto-Duarte, A., Poirion, O., Preissl, S., Purdom, E., Rimorin, C., Risso, D., Rivkin, A.C., Smith, K., Street, K., Sulc, J., Svensson, V., Tieu, M., Torkelson, A., Tung, H., Vaishnav, E.D., Vanderburg, C.R., van Velthoven, C., Wang, X., White, O.R., Huang, Z.J., Kharchenko, P.V., Pachter, L., Ngai, J., Regev, A., Tasic, B., Welch, J.D., Gillis, J., Macosko, E.Z., Ren, B., Ecker, J.R., Zeng, H., Mukamel, E.A. A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex. (2021) Nature. 598(7879):103-110. DOI: 10.1038/s41586-021-03500-8

+ expand abstract

Bakken, T.E., Jorstad, N.L., Hu, Q., Lake, B.B., Tian, W., Kalmbach, B.E., Crow, M., Hodge, R.D., Krienen, F.M., Sorensen, S.A., Eggermont, J., Yao, Z., Aevermann, B.D., Aldridge, A.I., Bartlett, A., Bertagnolli, D., Casper, T., Castanon, R.G., Crichton, K., Daigle, T.L., Dalley, R., Dee, N., Dembrow, N., Diep, D., Ding, S.L., Dong, W., Fang, R., Fischer, S., Goldman, M., Goldy, J., Graybuck, L.T., Herb, B.R., Hou, X., Kancherla, J., Kroll, M., Lathia, K., van Lew, B., Li, Y.E., Liu, C.S., Liu, H., Lucero, J.D., Mahurkar, A., McMillen, D., Miller, J.A., Moussa, M., Nery, J.R., Nicovich, P.R., Niu, S.Y., Orvis, J., Osteen, J.K., Owen, S., Palmer, C.R., Pham, T., Plongthongkum, N., Poirion, O., Reed, N.M., Rimorin, C., Rivkin, A., Romanow, W.J., Sedeño-Cortés, A.E., Siletti, K., Somasundaram, S., Sulc, J., Tieu, M., Torkelson, A., Tung, H., Wang, X., Xie, F., Yanny, A.M., Zhang, R., Ament, S.A., Behrens, M.M., Bravo, H.C., Chun, J., Dobin, A., Gillis, J., Hertzano, R., Hof, P.R., Höllt, T., Horwitz, G.D., Keene, C.D., Kharchenko, P.V., Ko, A.L., Lelieveldt, B.P., Luo, C., Mukamel, E.A., Pinto-Duarte, A., Preissl, S., Regev, A., Ren, B., Scheuermann, R.H., Smith, K., Spain, W.J., White, O.R., Koch, C., Hawrylycz, M., Tasic, B., Macosko, E.Z., McCarroll, S.A., Ting, J.T., Zeng, H., Zhang, K., Feng, G., Ecker, J.R., Linnarsson, S., Lein, E.S. Comparative cellular analysis of motor cortex in human, marmoset and mouse. (2021) Nature. 598(7879):111-119. DOI: 10.1038/s41586-021-03465-8

+ expand abstract

Gao, C., Liu, J., Kriebel, A.R., Preissl, S., Luo, C., Castanon, R., Sandoval, J., Rivkin, A., Nery, J.R., Behrens, M.M., Ecker, J.R., Ren, B., Welch, J.D. Iterative single-cell multi-omic integration using online learning. (2021) Nature Biotechnology. DOI: 10.1038/s41587-021-00867-x

+ expand abstract

Zhu, C., Zhang, Y., Li, Y.E., Lucero, J., Behrens, M.M., Ren, B. Joint profiling of histone modifications and transcriptome in single cells from mouse brain. (2021) Nature Methods. DOI: 10.1038/s41592-021-01060-3

+ expand abstract

Fang, R., Preissl, S., Li, Y., Hou, X., Lucero, J., Wang, X., Motamedi, A., Shiau, A.K., Zhou, X., Xie, F., Mukamel, E.A., Zhang, K., Zhang, Y., Behrens, M.M., Ecker, J.R., Ren, B. Comprehensive analysis of single cell ATAC-seq data with SnapATAC. (2021) Nature Communications. 12(1):1337. DOI: 10.1038/s41467-021-21583-9

+ expand abstract

Lavery, L.A., Ure, K., Wan, Y.W., Luo, C., Trostle, A.J., Wang, W., Jin, H., Lopez, J., Lucero, J., Durham, M.A., Castanon, R., Nery, J.R., Liu, Z., Goodell, M., Ecker, J.R., Behrens, M.M., Zoghbi, H.Y. Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome. (2020) Elife. 9. DOI: 10.7554/eLife.52981

+ expand abstract

Zhu, C., Yu, M., Huang, H., Juric, I., Abnousi, A., Hu, R., Lucero, J., Behrens, M.M., Hu, M., Ren, B. An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome. (2019) Nature Structural & Molecular Biology. 26:1063–1070. DOI: 10.1038/s41594-019-0323-x

+ expand abstract

Amodeo, D.A., Lai, C.Y., Hassan, O., Mukamel, E.A., Behrens, M.M., Powell, S.B. Maternal immune activation impairs cognitive flexibility and alters transcription in frontal cortex. (2019) Neurobiology of Disease. 125:211-218. DOI: 10.1016/j.nbd.2019.01.025

+ expand abstract

Luo, C., Rivkin, A., Zhou, J., Sandoval, J.P., Kurihara, L., Lucero, J., Castanon, R., Nery, J.R., Pinto-Duarte, A., Bui, B., Fitzpatrick, C., O’Connor, C., Ruga, S., Van Eden, M.E., Davis, D.A., Mash, D.C., Behrens, M.M., Ecker, J.R. Robust single-cell DNA methylome profiling with snmC-seq2. (2018) Nature Communications. 9(1):3824. DOI: 10.1038/s41467-018-06355-2

+ expand abstract

Wang, X., Pinto-Duarte, A., Behrens, M.M., Zhou, X., Sejnowski, T.J. Ketamine independently modulated power and phase-coupling of theta oscillations in Sp4 hypomorphic mice. (2018) PLOS One. 13(3):e0193446. DOI: 10.1371/journal.pone.0193446

+ expand abstract

Luo, C., Keown, C.L., Kurihara, L., Zhou, J., He, Y., Li, J., Castanon, R., Lucero, J., Nery, J.R., Sandoval, J.P., Bui, B., Sejnowski, T.J., Harkins, T.T., Mukamel, E.A.*, Behrens, M.M.*, Ecker, J.R.* Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex. (2017) Science. 357(6351):600-604. DOI: 10.1126/science.aan3351

+ expand abstract

Khan, A., de Jong, L.A., Kamenski, M.E., Higa, K.K., Lucero, J.D., Young, J.W., Behrens, M.M.*, Powell, S.B.* Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice. (2017) Neuroscience. 345:166-175. DOI: 10.1016/j.neuroscience.2016.11.022

+ expand abstract

Jadi, M.P., Behrens, M.M., Sejnowski, T.J. Abnormal Gamma Oscillations in N-Methyl-D-Aspartate Receptor Hypofunction Models of Schizophrenia. (2016) Biological Psychiatry. 79(9):716-26. DOI: 10.1016/j.biopsych.2015.07.005

+ expand abstract

Wang, X., Pinto-Duarte, A., Behrens, M.M., Zhou, X., Sejnowski, T.J. Characterization of spatio-temporal epidural event-related potentials for mouse models of psychiatric disorders. (2015) Scientific Reports. 5:14964. DOI: 10.1038/srep14964

+ expand abstract

Barnes, S.A., Pinto-Duarte, A., Kappe, A., Zembrzycki, A., Metzler, A., Mukamel, E.A., Lucero, J., Wang, X., Sejnowski, T.J., Markou, A.*, Behrens, M.M.* Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders. (2015) Molecular Psychiatry. 20(10):1161-72. DOI: 10.1038/mp.2015.113

+ expand abstract

Powell, S.B., Khan, A., Young, J.W., Scott, C.N., Buell, M.R., Caldwell, S., Tsan, E., de Jong, L.A., Acheson, D.T., Lucero, J., Geyer, M.A., Behrens, M.M. Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats. (2015) Developmental Neuroscience. 37(3):253-62. DOI: 10.1159/000430091

+ expand abstract

Lister, R.*, Mukamel, E.A., Nery, J.R., Urich, M., Puddifoot, C.A., Johnson, N.D., Lucero, J., Huang, Y., Dwork, A.J., Schultz, M.D., Yu, M., Tonti-Filippini, J., Heyn, H., Hu, S., Wu, J.C., Rao, A., Esteller, M., He, C., Haghighi, F.G., Sejnowski, T.J., Behrens, M.M.*, Ecker, J.R.* Global epigenomic reconfiguration during mammalian brain development. (2013) Science. 341(6146):1237905. DOI: 10.1126/science.1237905

+ expand abstract

Ji, B., Wang, X., Pinto-Duarte, A., Kim, M., Caldwell, S., Young, J.W., Behrens, M.M., Sejnowski, T.J., Geyer, M.A., Zhou, X. Prolonged Ketamine Effects in Sp4 Hypomorphic Mice: Mimicking Phenotypes of Schizophrenia. (2013) PLOS One. 8(6):e66327. DOI: 10.1371/journal.pone.0066327

+ expand abstract

Wang, X., Pinto-Duarte, A., Sejnowski, T.J., Behrens, M.M. How Nox2-containing NADPH oxidase affects cortical circuits in the NMDA receptor antagonist model of schizophrenia. (2013) Antioxidants & Redox Signaling. 18(12):1444-62. DOI: 10.1089/ars.2012.4907

+ expand abstract

Powell, S.B., Sejnowski, T.J., Behrens, M.M. Behavioral and neurochemical consequences of cortical oxidative stress on parvalbumin-interneuron maturation in rodent models of schizophrenia. (2012) Neuropharmacology. 62(3):1322-31. DOI: 10.1016/j.neuropharm.2011.01.049

+ expand abstract

Amitai, N., Kuczenski, R., Behrens, M.M., Markou, A. Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats. (2012) Neuropharmacology. 62(3):1422-31. DOI: 10.1016/j.neuropharm.2011.01.008

+ expand abstract

Volman, V., Behrens, M.M., Sejnowski, T.J. Downregulation of parvalbumin at cortical GABA synapses reduces network gamma oscillatory activity. (2011) Journal of Neuroscience. 31(49):18137-48. DOI: 10.1523/JNEUROSCI.3041-11.2011

+ expand abstract

Loomis, W.F., Behrens, M.M., Williams, M.E., Anjard, C. Pregnenolone sulfate and cortisol induce secretion of acyl-CoA-binding protein and its conversion into endozepines from astrocytes. (2010) Journal of biological chemistry. 285(28):21359-65. DOI: 10.1074/jbc.M110.105858

+ expand abstract

Kinney, J.W., Sanchez-Alavez, M., Barr, A.M., Criado, J.R., Crawley, J.N., Behrens, M.M., Henriksen, S.J., Bartfai, T. Impairment of memory consolidation by galanin correlates with in vivo inhibition of both LTP and CREB phosphorylation. (2009) Neurobiology of Learning and Memory. 92(3):429-38. DOI: 10.1016/j.nlm.2009.06.005

+ expand abstract

Behrens, M.M., Sejnowski, T.J. Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex? (2009) Neuropharmacology. 57(3):193-200. DOI: 10.1016/j.neuropharm.2009.06.002

+ expand abstract

Dugan, L.L., Ali, S.S., Shekhtman, G., Roberts, A.J., Lucero, J., Quick, K.L., Behrens, M.M. IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase. (2009) PLOS One. 4(5):e5518. DOI: 10.1371/journal.pone.0005518

+ expand abstract

Lodge, D.J., Behrens, M.M., Grace, A.A. A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. (2009) Journal of neuroscience . 29(8):2344-54. DOI: 10.1523/JNEUROSCI.5419-08.2009

+ expand abstract

Behrens, M.M., Ali, S.S., Dugan, L.L. Interleukin-6 mediates the increase in NADPH-oxidase in the ketamine model of schizophrenia. (2008) Journal of Neuroscience. 28(51):13957-66. DOI: 10.1523/JNEUROSCI.4457-08.2008

+ expand abstract

Zhang, Y., Behrens, M.M., Lisman, J.E. Prolonged exposure to NMDAR antagonist suppresses inhibitory synaptic transmission in prefrontal cortex. (2008) Journal of Neurophysiology. 100(2):959-65. DOI: 10.1152/jn.00079.2008

+ expand abstract

Behrens, M.M.*, Ali, S.S., Dao, D.N., Lucero, J., Shekhtman, G., Quick, K.L., Dugan, L.L.* Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase. (2007) Science. 318(5856):1645-7. DOI: 10.1126/science.1148045

+ expand abstract

Ali, S.S., Xiong, C., Lucero, J., Behrens, M.M., Dugan, L.L., Quick, K.L. Gender differences in free radical homeostasis during aging: shorter-lived female C57BL6 mice have increased oxidative stress. (2006) Aging Cell. 5(6):565-74. DOI: 10.1111/j.1474-9726.2006.00252.x

+ expand abstract

Davis, C.N., Tabarean, I., Gaidarova, S., Behrens, M.M., Bartfai, T. IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons. (2006) J. Neurochem. 98(5):1379-89. DOI: 10.1111/j.1471-4159.2006.03951.x

+ expand abstract

Davis, C.N., Mann, E., Behrens, M.M., Gaidarova, S., Rebek, M., Rebek, J., Bartfai, T. MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics. (2006) Proceedings of the National Academy of Sciences of the United States of America. 103(8):2953-8. DOI: 10.1073/pnas.0510802103

+ expand abstract

Sanchez-Alavez, M., Tabarean, I.V., Behrens, M.M., Bartfai, T. Ceramide mediates the rapid phase of febrile response to IL-1beta. (2006) Proceedings of the National Academy of Sciences of the United States of America. 103(8):2904-8. DOI: 10.1073/pnas.0510960103

+ expand abstract

Kinney, J.W., Davis, C.N., Tabarean, I., Conti, B., Bartfai, T., Behrens, M.M. A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons. (2006) Journal of Neuroscience. 26(5):1604-15. DOI: 10.1523/JNEUROSCI.4722-05.2006

+ expand abstract

Tabarean, I.V., Conti, B., Behrens, M.M., Korn, H., Bartfai. Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture (2005) Neuroscience. 135(2):433-449. DOI: https://doi.org/10.1016/j.neuroscience.2005.06.053

+ expand abstract

Badie-Mahdavi, H., Behrens, M.M., Rebek, J., Bartfai, T. Effect of galnon on induction of long-term potentiation in dentate gyrus of C57BL/6 mice. (2005) Neuropeptides. 39(3):249-51. DOI: 10.1016/j.npep.2004.12.010

+ expand abstract

Badie-Mahdavi, H., Lu, X., Behrens, M.M., Bartfai, T. Role of galanin receptor 1 and galanin receptor 2 activation in synaptic plasticity associated with 3′,5′-cyclic AMP response element-binding protein phosphorylation in the dentate gyrus: studies with (2005) Neuroscience. 133(2):591-604. DOI: 10.1016/j.neuroscience.2005.02.042

+ expand abstract

Conti, B., Sugama, S., Lucero, J., Winsky-Sommerer, R., Wirz, S.A., Maher, P., Andrews, Z., Barr, A.M., Morale, M.C., Paneda, C., Pemberton, J., Gaidarova, S., Behrens, M.M., Beal, F., Sanna, P.P., Horvath, T., Bartfai, T. Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity. (2005) Journal of Neurochemistry. 93(2):493-501. DOI: 10.1111/j.1471-4159.2005.03052.x

+ expand abstract

Lu, X., Barr, A.M., Kinney, J.W., Sanna, P., Conti, B., Behrens, M.M., Bartfai, T. A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. (2005) Proceedings of the National Academy of Sciences of the United States of America. 102(3):874-9. DOI: 10.1073/pnas.0408891102

+ expand abstract

Dubé, C., Vezzani, A., Behrens, M., Bartfai, T., Baram, T.Z. Interleukin-1beta contributes to the generation of experimental febrile seizures. (2005) Ann. Neurol. 57(1):152-5. DOI: 10.1002/ana.20358

+ expand abstract

Tabarean, I.V., Behrens, M.M., Bartfai, T., Korn, H. Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition. (2004) Proceedings of the National Academy of Sciences of the United States of America. 101(8):2590-5. DOI: 10.1073/pnas.0308718101

+ expand abstract

Kim, H.J., Hwang, J.J., Behrens, M.M., Snider, B.J., Choi, D.W., Koh, J.Y. TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture. (2003) Neurobiol. Dis. 14(1):110-9.

+ expand abstract

Viviani, B., Bartesaghi, S., Gardoni, F., Vezzani, A., Behrens, M.M., Bartfai, T., Binaglia, M., Corsini, E., Di Luca, M., Galli, C.L., Marinovich, M. Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases. (2003) Journal of Neuroscience. 23(25):8692-700.

+ expand abstract

Bartfai, T., Behrens, M.M., Gaidarova, S., Pemberton, J., Shivanyuk, A., Rebek, J. A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses. (2003) Proceedings of the National Academy of Sciences of the United States of America. 100(13):7971-6. DOI: 10.1073/pnas.0932746100

+ expand abstract

Heidinger, V., Manzerra, P., Wang, X.Q., Strasser, U., Yu, S.P., Choi, D.W., Behrens, M.M. Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons. (2002) Journal of Neuroscience. 22(13):5452-61. DOI: 20026565

+ expand abstract

Manzerra, P., Behrens, M.M., Canzoniero, L.M., Wang, X.Q., Heidinger, V., Ichinose, T., Yu, S.P., Choi, D.W. Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity. (2001) Proceedings of the National Academy of Sciences of the United States of America. 98(20):11055-61. DOI: 10.1073/pnas.191353598

+ expand abstract

Moreno-Bueno, G., Calés, C., Behrens, M.M., Fernández-Renart, M. Isolation and characterization of casein kinase I from Dictyostelium discoideum. (2000) Biochemical Journal. 349(Pt 2):527-37. DOI: 10.1042/0264-6021:3490527

+ expand abstract

Sheline, C.T., Behrens, M.M., Choi, D.W. Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis. (2000) Journal of Neuroscience. 20(9):3139-46.

+ expand abstract

Behrens, M.M., Strasser, U., Heidinger, V., Lobner, D., Yu, S.P., McDonald, J.W., Won, M., Choi, D.W. Selective activation of group II mGluRs with LY354740 does not prevent neuronal excitotoxicity. (1999) Neuropharmacology. 38(10):1621-30. DOI: 10.1016/s0028-3908(99)00098-2

+ expand abstract

Behrens, M.M., Strasser, U., Koh, J.Y., Gwag, B.J., Choi, D.W. Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase. (1999) Neuroscience. 94(3):917-27. DOI: 10.1016/s0306-4522(99)00212-2

+ expand abstract

Behrens, M.M., Strasser, U., Lobner, D., Dugan, L.L. Neurotrophin-mediated potentiation of neuronal injury. (1999) Microsc. Res. Tech. 45(4-5):276-84. DOI: 10.1002/(SICI)1097-0029(19990515/01)45:4/5<276::AI

+ expand abstract

Behrens, M.M., Strasser, U., Choi, D.W. Gö 6976 is a potent inhibitor of neurotrophin-receptor intrinsic tyrosine kinase. (1999) J. Neurochem. 72(3):919-24. DOI: 10.1046/j.1471-4159.1999.0720919.x

+ expand abstract

García-Gallo, M., Behrens, M.M., Renart, J., Díaz-Guerra, M. Expression of N-methyl-D-aspartate receptors using vaccinia virus causes excitotoxic death in human kidney cells. (1999) J. Cell. Biochem. 72(1):135-44.

+ expand abstract

Strasser, U., Lobner, D., Behrens, M.M., Canzoniero, L.M., Choi, D.W. Antagonists for group I mGluRs attenuate excitotoxic neuronal death in cortical cultures. (1998) European Journal of Neuroscience. 10(9):2848-55. DOI: 10.1111/j.1460-9568.1998.00291.x

+ expand abstract

Martínez, J.L., Behrens, M.M., Moratilla, C., Renart, J. Oleoylanilide, a possible causative agent of toxic oil syndrome, interferes with the cytoskeleton in a neuronal cell line. (1997) Neurotoxicology and Teratology. 19(2):147-50.

+ expand abstract

Boland, K., Behrens, M., Choi, D., Manias, K., Perlmutter, D.H. The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide. (1996) Journal of Biological Chemistry. 271(30):18032-44. DOI: 10.1074/jbc.271.30.18032

+ expand abstract

Hewett, S.J., Misko, T.P., Keeling, R.M., Behrens, M.M., Choi, D.W., Cross, A.H. Murine encephalitogenic lymphoid cells induce nitric oxide synthase in primary astrocytes. (1996) Journal of Neuroimmunology. 64(2):201-8.

+ expand abstract

Gwag, B.J., Koh, J.Y., Chen, M.M., Dugan, L.L., Behrens, M.M., Lobner, D., Choi, D.W. BDNF or IGF-I potentiates free radical-mediated injury in cortical cell cultures. (1995) Neuroreport. 7(1):93-6.

+ expand abstract

Behrens, M.M., Martínez, J.L., Moratilla, C., Renart, J. Apoptosis induced by protein kinase C inhibition in a neuroblastoma cell line. (1995) Cell Growth & Differentiation. 6(11):1375-80.

+ expand abstract

Franco, E., Behrens, M.M., Díaz-Guerra, M., Renart, J. Structure and expression of a polyubiquitin gene from the crustacean Artemia. (1994) Gene Expression. 4(1-2):19-28.

+ expand abstract

Mazón, M.J., Behrens, M.M., Morgado, E., Portillo, F. Low activity of the yeast cAMP-dependent protein kinase catalytic subunit Tpk3 is due to the poor expression of the TPK3 gene. (1993) European Journal of Biochemistry. 213(1):501-6. DOI: 10.1111/j.1432-1033.1993.tb17787.x

+ expand abstract

Schwandner, W.R., Jiménez, B., Schwartz, A., Weijer, C.J., Behrens, M., Mazón, M.J., Fernández-Renart, M. Chemotactic stimulation of aggregation-stage Dictyostelium cells induces rapid changes in energy metabolism, as measured by succinic thiokinase phosphorylation. (1993) Biochimica et Biophysica Acta. 1176(1-2):175-82. DOI: 10.1016/0167-4889(93)90194-t

+ expand abstract

Mazón, M.J., Behrens, M.M., Portillo, F., Piñón, R. cAMP- and RAS-independent nutritional regulation of plasma-membrane H+-ATPase activity in Saccharomyces cerevisiae. (1989) J. Gen. Microbiol. 135(6):1453-60. DOI: 10.1099/00221287-135-6-1453

+ expand abstract

Behrens, M.M., Mazón, M.J. Yeast cAMP-dependent protein kinase can be associated to the plasma membrane. (1988) Biochemical and Biophysical Research Communications. 151(1):561-7. DOI: 10.1016/0006-291x(88)90631-6

+ expand abstract